Professor, Department of Obstetrics and Gynecology, OUHSC Adjunct Professor, Biochemistry and Molecular Biology, OUHSC Member, Stephenson Cancer Center
Director of Research, Section of Gynecologic Oncology, OUHSC
Chair in Gynecologic Oncology, OUHSC
Editor-in-Chief, Biologics: Targets and Therapy
See Also: Department of Obstetrics and Gynecology Department of Biochemistry and Molecular Biology Benbrook Lab Website
Research Expertise: Drug Discovery and Development, Cell Death, Autophagy, Biomarkers, Chemoprevention, Gyn/Onc
Research Description: My research group developed a non-toxic cancer prevention drug that is currently in the clinical trial planning stage. All of the preclinical testing required for FDA approval to initiate clinical trials has been completed. My main current focus is to understand the molecular mechanism of this drug and to develop improved analogs. Another aspect of my research is studying the dynamic process of carcinogenesis and chemoprevention using a 3-D organotypic model and systems biology. The most translational aspect of my research is studying biomarkers in clinical specimens from GYN/ONC clinical trials for prognostic, predictive and diagnostic value.