Core Services The Biospecimen Acquisition Core and Bank at the Stephenson Cancer Center provides the following services to SCC members and other interested investigators:
Types and availability of samples differ by organ type. Users are encouraged to contact the Core for more information. If appropriate specimens are not available in the Biospecimen Bank, Core staff will help facilitate the procurement of specimens from the appropriate sources. The Core also supports protocol-driven specimen collection for specific research projects.
About the Core
The SCC Biospecimen Acquisition Core and Bank was established in 2006 when the SCC assumed management of the Dawn Hope Tissue Bank, a large collection of gynecologic tissue samples. Since that time the Core has provided specimen collection, storage and processing services to SCC members and other investigators. The Core’s Biospecimen Bank currently contains over 30,000 aliquotted samples collected since 2008, including tissue, blood, plasma, serum, cell and buccal samples. The Core utilizes an IRB-approved Universal Consent that allows patients at SCC, OU Physicians or OU Medical Center to donate tissue or blood to the Biospecimen Bank. Over 3,500 patients have consented to participate since 2008. The Core has especially large specimen collections of gynecologic cancers and pancreatic cancer to support research in those disease sites.
The Core also provides specimen collection, processing and shipping services to a large and active clinical research program at the SCC. Since 2008 the Core has supported over 300 clinical trials, including large tissue trials such as GOG 136, GOG 210, GOG 221 and NCI’s SUCCEED trial, for which the SCC was the lead tissue site in each. A dedicated PK processing room supports the SCC’s Phase I clinical trials program.
In 2012 the SCC was selected as a Tissue Source Site for The Cancer Genome Atlas (TCGA) Project. TCGA researchers are identifying the genomic changes in more than 20 different types of human cancer. By comparing the DNA in samples of normal tissue and cancer tissue taken from the same patient, researchers can identify changes specific to that particular cancer. By connecting specific genomic changes with specific outcomes, researchers will be able to develop more effective, individualized ways of helping each cancer patient.
For more information about the TCGA see: http://cancergenome.nih.gov/
The Core’s main facility is on the fourth floor of the Stanton L. Young Biomedical Research Center (BRC) on the OUHSC campus. A satellite facility on the third floor of the SCC building is dedicated to supporting the SCC’s Phase I clinical trials program with specimen processing and shipping services. Core Information Systems
In conjunction with the SCC's Clinical Trials Office, the Biospecimen Acquisition Core and Bank uses a HIPAA and 21 CFR Part 11 compliant clinical trials management system (Velos eResearch). An integrated specimen inventory system (Velos eSample) is used to catalog banked specimens. Data are stored on a secure server with access limited to key protocol personnel.
If research supported by the Biospecimen Acquisition Core and Bank results in a publication, please acknowledge this support by including the following in your manuscript: "We thank the Peggy and Charles Stephenson Cancer Center for the use of the Biospecimen Core, which provided _______ service."
For more information please contact:
Biospecimen Acquisition Core and Bank