Recent Publications of the Department
Overexpression of Retinal Degeneration Slow (RDS) Protein Adversely Affects Rods in the rd7 Model of Enhanced S-Cone Syndrome. Chakraborty D, Conley SM, Naash MI. PLoS One. 2013 May 1;8(5):e63321. doi: 10.1371/journal.pone.0063321. Print 2013. PMID:23650562
KDM4/JMJD2 Histone Demethylases: Epigenetic Regulators in Cancer Cells. Berry WL, Janknecht R. Cancer Res. 2013 May 3. PMID:23644528
Bone marrow endothelial progenitors in atherosclerotic plaque resolution.
Yao L, Heuser-Baker J, Herlea-Pana O, Barlic-Dicen J. Organogenesis. 2013 Jan 1;9(1). PMID: 23538778
The choroid as a sclera growth regulator.
Summers JA. Exp Eye Res. 2013 Mar 23. doi:pii: S0014-4835(13)00062-6. 10.1016/j.exer.2013.03.008. PMID: 23528534
Deciphering mutant ELOVL4 activity in autosomal-dominant Stargardt macular dystrophy.
Logan S, Agbaga MP, Chan MD, Kabir N, Mandal NA, Brush RS, Anderson RE. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5446-51. doi: 10.1073/pnas.1217251110. Epub 2013 Mar 18. PMID: 23509295
LPA Stimulates the Phosphorylation of p130Cas via Gαi2 in Ovarian Cancer Cells.
Ward JD, Dhanasekaran DN. Genes Cancer. 2012 Sep;3(9-10):578-91. doi: 10.1177/1947601913475360. PMID: 23486563
Medaka fish, Oryzias latipes, as a model for human obesity-related glomerulopathy.Ichimura K, Kawashima Y, Nakamura T, Powell R, Hidoh Y, Terai S, Sakaida I, Kodera Y, Tsuji T, Ma JX, Sakai T, Matsumoto H, Obara T. Biochem Biophys Res Commun. 2013 Feb 22;431(4):712-7. doi: 10.1016/j.bbrc.2013.01.053. Epub 2013 Jan 23. PMID: 23353086
S/MAR-containing DNA nanoparticles promote persistent RPE gene expression and improvement in RPE65-associated LCA.
Koirala A, Makkia RS, Conley SM, Cooper MJ, Naash MI. Hum Mol Genet. 2013 Apr 15;22(8):1632-42. doi: 10.1093/hmg/ddt013. Epub 2013 Jan 18. PMID: 23335596
Developmental localization of nephrin in zebrafish and medaka pronephric glomerulus.Ichimura K, Fukuyo Y, Nakamura T, Powell R, Sakai T, Janknecht R, Obara T. J Histochem Cytochem. 2013 Apr;61(4):313-24. doi: 10.1369/0022155413477115. Epub 2013 Jan 15. PMID: 23324868
Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors.Wickham S, Regan N, West MB, Thai J, Cook PF, Terzyan SS, Li PK, Hanigan MH. Biochem J. 2013 Mar 15;450(3):547-57. doi: 10.1042/BJ20121435. PMID: 23301618
Role of melatonin and its receptors in the vertebrate retina.
Wiechmann AF, Sherry DM. Int Rev Cell Mol Biol. 2013;300:211-42. doi: 10.1016/B978-0-12-405210-9.00006-0. PMID: 23273863
Comparative analysis of DNA nanoparticles and AAVs for ocular gene delivery.
Han Z, Conley SM, Makkia R, Guo J, Cooper MJ, Naash MI. PLoS One. 2012;7(12):e52189. doi: 10.1371/journal.pone.0052189. Epub 2012 Dec 18. PMID: 23272225
Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition.Tomasek JJ, Haaksma CJ, Schwartz RJ, Howard EW. Wound Repair Regen. 2013 Jan-Feb;21(1):166-76. doi: 10.1111/wrr.12001. Epub 2012 Dec 18. PMID: 23253249
Retinal angiogenesis in the Ins2(Akita) mouse model of diabetic retinopathy.Han Z, Guo J, Conley SM, Naash MI. Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):574-84. doi: 10.1167/iovs.12-10959. PMID: 23221078 Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis.Bubenshchikova E, Ichimura K, Fukuyo Y, Powell R, Hsu C, Morrical SO, Sedor JR, Sakai T, Obara T. Biol Open. 2012 Jun 15;1(6):588-96. doi: 10.1242/bio.20121016. Epub 2012 May 4. PMID: 23213452
Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.
Pasula S, Cai X, Dong Y, Messa M, McManus J, Chang B, Liu X, Zhu H, Mansat RS, Yoon SJ, Hahn S, Keeling J, Saunders D, Ko G, Knight J, Newton G, Luscinskas F, Sun X, Towner R, Lupu F, Xia L, Cremona O, De Camilli P, Min W, Chen H. J Clin Invest. 2012 Dec 3;122(12):4424-38. doi: 10.1172/JCI64537. Epub 2012 Nov 26. PMID: 23187125
Structural characterization of the second intra-discal loop of the photoreceptor tetraspanin RDS.
Chakraborty D, Rodgers KK, Conley SM, Naash MI. FEBS J. 2013 Jan;280(1):127-38. doi: 10.1111/febs.12055. Epub 2012 Nov 22. PMID: 23121719
Bone marrow endothelial progenitors augment atherosclerotic plaque regression in a mouse model of plasma lipid lowering.
Yao L, Heuser-Baker J, Herlea-Pana O, Iida R, Wang Q, Zou MH, Barlic-Dicen J. Stem Cells. 2012 Dec;30(12):2720-31. doi: 10.1002/stem.1256. PMID: 23081735
ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells.
Shin S, Oh S, An S, Janknecht R. Oncol Rep. 2013 Jan;29(1):306-14. doi: 10.3892/or.2012.2079. Epub 2012 Oct 16. PMID: 23076342
A comparative analysis of glomerulus development in the pronephros of medaka and zebrafish.
Ichimura K, Bubenshchikova E, Powell R, Fukuyo Y, Nakamura T, Tran U, Oda S, Tanaka M, Wessely O, Kurihara H, Sakai T, Obara T. PLoS One. 2012;7(9):e45286. doi: 10.1371/journal.pone.0045286. Epub 2012 Sep 18. PMID: 23028906
Structural disorganization of pronephric glomerulus in zebrafish mpp5a/nagie oko mutant.
Ichimura K, Fukuyo Y, Nakamura T, Powell R, Sakai T, Obara T. Dev Dyn. 2012 Dec;241(12):1922-32. doi: 10.1002/dvdy.23877. Epub 2012 Oct 25. PMID: 23027442
Oncogenic features of the JMJD2A histone demethylase in breast cancer.
Berry WL, Shin S, Lightfoot SA, Janknecht R. Int J Oncol. 2012 Nov;41(5):1701-6. doi: 10.3892/ijo.2012.1618. Epub 2012 Sep 4. PMID: 22948256
Cohesin acetylation promotes sister chromatid cohesion only in association with the replication machinery.
Song J, Lafont A, Chen J, Wu FM, Shirahige K, Rankin S. J Biol Chem. 2012 Oct 5;287(41):34325-36. doi: 10.1074/jbc.M112.400192. Epub 2012 Aug 15. PMID: 22896698
Therapeutic potential of a monoclonal antibody blocking the Wnt pathway in diabetic retinopathy.
Lee K, Hu Y, Ding L, Chen Y, Takahashi Y, Mott R, Ma JX. Diabetes. 2012 Nov;61(11):2948-57. doi: 10.2337/db11-0300. Epub 2012 Aug 13. PMID: 22891217
DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice.
Han Z, Conley SM, Makkia RS, Cooper MJ, Naash MI. J Clin Invest. 2012 Sep 4;122(9):3221-6. doi: 10.1172/JCI64833. Epub 2012 Aug 13. PMID: 22886305
Characterization of the interactions of mammalian RNA polymerase I associated proteins PAF53 and PAF49.
Penrod Y, Rothblum K, Rothblum LI. Biochemistry. 2012 Aug 21;51(33):6519-26. doi: 10.1021/bi300408q. Epub 2012 Aug 8. PMID: 22849406
Differential developmental deficits in retinal function in the absence of either protein tyrosine sulfotransferase-1 or -2.
Sherry DM, Kanan Y, Hamilton R, Hoffhines A, Arbogast KL, Fliesler SJ, Naash MI, Moore KL, Al-Ubaidi MR. PLoS One. 2012;7(6):e39702. doi: 10.1371/journal.pone.0039702. Epub 2012 Jun 22. PMID: 22745813
Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina.
Vuong L, Brobst DE, Saadi A, Ivanovic I, Al-Ubaidi MR. Invest Ophthalmol Vis Sci. 2012 Jul 20;53(8):4821-31. doi: 10.1167/iovs.11-8681. PMID: 22714890
Meiotic chromosome pairing is promoted by telomere-led chromosome movements independent of bouquet formation.
Lee CY, Conrad MN, Dresser ME. PLoS Genet. 2012;8(5):e1002730. doi: 10.1371/journal.pgen.1002730. Epub 2012 May 24. PMID: 22654677
Great expectations--or how to focus on prevention for all.
O'Donoghue DL. JAAPA. 2012 Mar;25(3):12. No abstract available. PMID: 22514951
Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency.
Thapa A, Morris L, Xu J, Ma H, Michalakis S, Biel M, Ding XQ. J Biol Chem. 2012 May 25;287(22):18018-29. doi: 10.1074/jbc.M112.342220. Epub 2012 Apr 9. PMID: 22493484
Biol Open. 2012 Jun 15;1(6):588-96. doi: 10.1242/bio.20121016. Epub 2012 May 4. Yao L, Heuser-Baker J, Herlea-Pana O, Iida R, Wang Q, Zou MH, Barlic-Dicen J.
Biol Open. 2012 Jun 15;1(6):588-96. doi: 10.1242/bio.20121016. Epub 2012 May 4. Yao L, Heuser-Baker J, Herlea-Pana O, Iida R, Wang Q, Zou MH, Barlic-Dicen J.