myers-dean-2_48577702517_o
Dean A. Myers, Ph.D.

Roles

  • Professor
  • John W. Records Chair in Maternal-Fetal Medicine
  • Director of Research, MFM Fellowship
  • Member, Harold Hamm Diabetes Center

Education

  • B.S., Animal Science, Fort Hays State University (KS), 1981
  • M.S., Reproductive Physiology, University of Wyoming, 1983
  • Ph.D., Reproductive Physiology/Biochemistry, University of Wyoming, 1987
  • Post-doctoral Fellowship, Cornell University, 1987-1990

Research Interests

  • Impact of gestational hypoxia on fetal physiology, endocrinology and adipose development
  • Impact of maternal obesity on fetal CNS development
  • Maternal Zika virus infection and fetal CNS pathology using a non-human primate model (baboon)

Organizations

  • Society for Reproductive Investigation
  • Perinatal Research Society
  • Endocrine Society
  • American Physiological Society

Awards/Honors (selected)

  • President’s Associates Presidential Professorship, OUHSC, 2009-2013   
  • Member: Harold Hamm Diabetes Center, OUHSC, 2014-current
  • NIH CSR Rapid assessment of Zika virus complications. ZAI1 M M3-RG, 5/2017             
  • NIH CSR Dual Purpose with Dual Benefit: Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Animal Species. 2017/05 ZRG1 IDM-N(50)S, 3/2017
  • NIH CSR Pregnancy and Neonatology (PN) Study Section, 10/2016
  • NIH CSR Special Emphasis Panel, PAR13-309-311: Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics, ZRGI EMNR-S, 6/2016            
  • NIH CSR Special Emphasis Panel, ZRGI EMNR-A, 7/2015            
  • NIH CSR Integrative, Clinical Endocrinology and Metabolism (ICER) Study Section, 2/2015      
  • NIH CSR Pregnancy and Neonatology (PN) Study Section, 6/2014          
  • NIH CSR Endocrinology, Metabolism, Nutrition and Reproductive Sciences Small Business/Technology Transfer (SBIR/STTR) Study Section, 6/2014            
  • Chair and Reviewer, NIH CSR Endocrinology, Metabolism, Nutrition and Reproductive Sciences Small Business/Technology Transfer (SBIR/STTR) Study Section, Special Emphasis Panel, NIH CSR ZRG1 EMNR-S 11 B, 12/2013          
  • Regular Member, NIH CSR Pregnancy and Neonatology (PN) Study Section, 2008-2012
  • Chair, NIH CSR PAR Panel: Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Animal Species. ZRG1 EMNR-D, 3/2012          
  • NIH CSR Special Emphasis Panel: Developmental Pharmacology, NIH ZRG1, CB-L, 8/2011            
  • NIH CSR NICHD Program Project Review, ZHD1 DSR-Z, 4/2011            
  • NIH CSR NICHD Program Project Review, ZHD1 DSR-Z, 4/2010            
  • NIH CSR Neuroendocrin., Neuroimmun. & Behavior (NNB) Study Section, 2/2010              
  • NIH CSR Neuroendocrin., Neuroimmun. & Behavior (NNB) Study Section, 6/2009          
  • NIH CSR Neuroendocrin., Neuroimmun. & Behavior (NNB) Study Section, 10/2009          
  • NIH CSR, Special Emphasis Panel-Pregnancy and Developmental Biology, 7/2008           
  • NIH CSR, Special Emphasis Panel-Pregnancy and Neonatology, EMNR ZRG1, 7/2007
  • NIH CSR Pregnancy and Neonatology (PN) study section,  2/2007          
  • NIMH CSR Conte Centers for Neuroscience, 2/2005         
  • NIH CSR Human Embryology and Development (HED-1), 2/2002:           

Publications

Complete List of Published Work in My Bibliography:

https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/47967746/?sort=date&direction=ascending

Selected Publications:

Gurung S, Reuter N, Preno AN, Dubaut JP, Nadeau H, Hyatt K, Singleton K, Marti A, Parks WT, Papin JF, Myers DA. 2019. Zika virus infection at mid-gestation results in fetal cerebral cortical injury and fetal death in the olive baboon. PLoS Pathogens 15(1): e1007507.   https://doi.org/10.1371/journal.ppat.1007507

Gurung S, Preno AN, Dubaut JP, Nadeau H, Hyatt K, Reuter N, Nehete B, Wolf RF, Nehete P, Dittmer DP, Myers DA, Papin JF. 2018. Translational model of Zika virus infection in baboons. J. Virology Jun 6. pii: JVI.00186-18. doi: 10.1128/JVI.00186-18. PMID:29875247

Vargas VE, Gurung S, Grant B, Hyatt, K, Singleton K, Myers SM, Saunders D, Njoku C, Towner R, Myers DA. 2017. Gestational hypoxia disrupts the neonatal leptin surge and programs hyperphagia and obesity in male offspring in the Sprague-Dawley rat. PLoS ONE. (PMID: 28957383)  

Vargus V. Singleton K, Kaushal KM, Myers DA, Ducsay CA. 2017. Expression of StAR and Key Genes Regulating Cortisol Biosynthesis in Near Term Ovine Fetal Adrenocortical Cells: Effects of Long Term Hypoxia. Reprod. Sci. Accepted

Gurung S. Agbaga M-P, Myers DA. 2016. Cognitive differences between Sprague-Dawley rats selectively bred for sensitivity or resistance to diet induced obesity. Behavioral Brain Research. 311:122-30. PMID: 27173431

Myers DA, Singleton K, Kenkel C, Kaushal KM, Ducsay CA. 2016. Gestational hypoxia modulates expression of corticotropin releasing hormone and arginine vasopressin in the hypothalamic paraventricular nucleus in the ovine fetus. Physiological Reports. Jan; 4(1). pii:e12643.doi: 10.14814/phy2.12643.

Jackson D, Deschamps D, Myers D, Fields D, Knudtson E, Gunatilake R. 2016. Fetal epicardial fat thickness in diabetic and non-diabetic pregnancies: a retrospective cross sectional study. Obesity. Jan; 24(1):167-71. PMID: 26638197

Newby EA, Myers DA, Ducsay CA. 2015. Fetal endocrine and metabolic adaptations to hypoxia: the role of the hypothalamic-pituitary-adrenal axis. Am. J. Physiol. Endocrinol. Metab. 309:E429-39. PMID: 26173460

Newby EA, Kashal KM, Myers DA, Ducsay CA. 2015. ACTH and PI3K/Akt inhibition reduce eNOS phosphorylation and increase cortisol biosynthesis in long term hypoxic ovine fetal adrenal cells. Reprod. Sciences 22:932-41. PMID: 25656500

Myers DA, Singleton K, Hyatt K, Mlynarczyk M, Kaushal K, Ducsay DA. 2015. Long term gestational hypoxia modulates expression of key genes governing mitochondrial function and biogenesis in the perirenal adipose of the late gestation sheep fetus. Reprod. Sciences 22:654-663. PMID: 25504105

Myers DA, Ducsay CA. 2014. Altitude, attitude and adaptation. Adv. Exp. Med. Biol. 814:147-57. PMID: 25015808