Unexplained Infertility

Assessment of Multiple Intrauterine Gestations from Ovarian Stimulation (AMIGOS)


We are currently involved in a double-blind research study, sponsored by the Reproductive Medicine Network and National Institute of Child Health and Human Development, to determine which medications are most likely to result in a pregnancy.

This research study is for patients between the ages of 18 and 40 who have had difficulty conceiving and is available at no cost to patients. 

Interested participants will go through a screening process to see if they qualify. 


The screening will include:

  • Blood Work (checking hormone levels, kidney function, and liver function)
  • Hysterosalpingogram or Sonohysterogram Tests
  • Pap Smear and Physical Exam
  • Seman Analysis on Partner

After passing the screening, the patient will be: 

  • Randomized, similar to the toss of a coin, to receive one of the medications. This is a double-blind study so neither the patient nor the doctor will know which medication the patient received.

  • Given a study medication and instructions on when to take the medication. Study medication will be taken at a specific time during each month and will be taken for a maximum period of 4 or 5 cycles or until becoming pregnant.

If you are interested in this study, please contact the Study Coordinators at (405)-271-1615

IRB #15280
This study is sponsored by the Reproductive Medicine Network and National Institute of Child Health and Human Development.