Celeste R. Wirsig-Wiechmann


Associate Professor, Department of Cell Biology


B.A., Psychology, Wells College, Aurora New York
Ph.D., in Neuroscience, University of Florida, Gainesville Florida 


Our multidisciplinary neuroscience laboratory uses a variety of research tools to understand the modulation of brain systems, particularly sensory systems, by hormones and/or the immune system. Hormones can alter our perception of the world and how we react to stimuli. In addition, our immune system is intimately associated with the nervous system and can either facilitate or inhibit neural systems. Our past research interests have involved the effects of the gonadotropin releasing hormone system on the chemosensory systems. We have also studied how the brain processes pheromone information. Our current research focuses on how the production of antibodies to certain neurotransmitter receptors can affect the olfactory system. This research is being conducted with the use of neuroanatomical, molecular biological, electrophysiological and behavioral techniques. We use many vertebrate species in order to develop generalizable concepts. Our research has been funded by the University of Oklahoma College of Medicine Alumni Association, Oklahoma Center for the Advancement of Science and Technology, the National Institute of Health and the National Science Foundation.


Wirsig-Wiechmann CR, Colvard J, Aston C, Dighe R, Houck LD, PW Feldhoff, Feldhoff  RC. 2012 Gonadotropin-releasing hormone modulates vomeronasal neuron response to male salamander pheromone. J. Experimental Neuroscience, 1: 1-10

Wirsig-Wiechmann, CR, Houck LD, Wood JM, Feldhoff PM, Feldhoff  RC 2006 Male Pheromone Protein Components Activate Female Vomeronasal Neurons in the Salamander Plethodon shermani, BMC Neuroscience, 7: 26.

Wirsig-Wiechmann, C.R., Houck, L.D., Feldhoff, P.W. and Feldhoff, F.C. 2002 Pheromonal activation of vomeronasal neurons in plethodontid salamanders. Brain Research Interactive, 952: 335-344.

Wirsig-Wiechmann, C.R. and Oka, Y. 2002 The terminal nerve ganglion projects to the olfactory mucosa in the dwarf gourami. Neurosci. Res. 44: 337-341.

Wirsig-Wiechmann, C.R. and Wiechmann, A.F. 2002 The vole retina is a target for gonadotropin-releasing hormone. Brain Research, 950: 210-217.

Wirsig-Wiechmann, C.R. and Ebadifar, B. 2002 Innervation of the naris constrictor muscle in tiger salamanders: an immunocytochemical study. Anat. Embryol. 205: 181-186.

Wirsig-Wiechmann, C.R. and. Holliday, K.R. 2002 Innervation of the naris constrictor muscle in tiger salamanders: a tracing study using biocytin. Anat. Embryol. 205: 169-179.

Wirsig-Wiechmann CR and Wiechmann AF 2001 The prarie vole vomeronasal organ is a target for gonadotropin-releasing hormone. Chem Senses 26: 1193-1202.

Koza, J.M. and Wirsig-Wiechmann, C.R. 2001 A subpopulation of nervus terminalis neurons projects to the olfactory mucosa in Xenopus laevis. J. Neurosci. Res. 66: 8-15.

Eisthen, H.L., Delay, R.J., Wirsig-Wiechmann, C.R., and Dionne, V.E. 2000  Neuromodulatory Effects of Gonadotropin Releasing Hormone on Olfactory Receptor Neurons. J. Neurosci. 20: 3947-3955.



University of Oklahoma Health Sciences Center 
Department of Cell Biology
P.O. Box 26901
Oklahoma City, OK 73126-0901
Phone: (405) 271-8001 ext. 47953
Fax: (405) 271-3548