T-cell Acute Lymphoblastic Leukemia (T-ALL)  panel

   

 Cancer of T-cells. Precursors to white blood cells are called blasts and are made by the bone marrow but in ALL the blasts are abnormal and do not develop into lymphocytes. Instead, the abnormal blasts or leukemic cells multiply rapidly and reduce the level of other types of blood cells such as red blood cells and platelets.

Common chromosome changes:

BCR/ABL t(9;22)(q34;q11.2)
MLL  11q23 rearrangements
TCR alpha/delta  14q11 rearrangements

Methodology: Fluorescent in Situ Hybridization (FISH) Analysis

Purpose: Confirmation of Clinical Diagnosis/Monitor During Treatment

ICD-9 Diagnosis: 204.00

Test Requisition: Cancer Cytogenetics Requisition

CPT Codes: 88271, 88275, 88291 Cost: $341.00 one probe

Turn-around-time: 2-5 days