Stavros Stavrakis, MD., Ph. D.

University of Oklahoma Health Sciences Center
Department of Medicine/Cardiovascular Section
Heart Rhythm Institute
1200 Everett Dr. TCH 6E103, 
Oklahoma City, OK 73104
Phone: 405-​271-9696
stavros-stavrakis@ouhsc.edu


Education:

08/2009-07/2011: 

University of Oklahoma Health Sciences Center Graduate College
Master of Science in Clinical and Translational Sciences

01/2003-12/2010:

University of Athens Medical School, Greece
Doctor of Philosophy, summa cum laude

10/1996-12/2002:

University of Athens Medical School, Greece 
Doctor of Medicine, summa cum laude

Medical Licensure:

07/2005:

Oklahoma State Board of Medical Licensure and Supervision

04/2003:

Licensed in Greece

Certification:

11/2011: 

ABIM Certification in Cardiology

08/2008:

ABIM Certification in Internal Medicine

02/2005:

ECFMG Certificate

Professional training:

07/2011-06/2012:

University of Oklahoma Health Sciences Center
Fellowship in Clinical Cardiac Electrophysiology

07/2008-06/2011:

University of Oklahoma Health Sciences Center
Fellowship in Cardiology

07/2005-06/2008:

University of Oklahoma Health Sciences Center
Residency in Internal Medicine

01/2003-06/2005:

University of Athens Medical School
Research Fellow

Academic Appointments:

07/2012-present:

Assistant Professor of Medicine, University of Oklahoma Health Sciences Center

Professional Membership:
American Heart Association, Council on Basic Cardiovascular Sciences
American College of Cardiology
Heart Rhythm Society


Honor Societies:

Phi Kappa Phi
Alpha Epsilon Lambda

Awards: 
American College of Cardiology Oklahoma Chapter 2012 Annual Scientific Meeting Best Poster Award, April 14 2012, Oklahoma City, OK
Manohar Sai Gowda Memorial Young Investigator Cardiovascular Research Award, 2011 Kansas City Heart Rhythm Symposium, August 27-28, 2011, Kansas City, MO
American College of Cardiology Oklahoma Chapter 2011 Annual Scientific Meeting Best Poster Award, April 16 2011, Oklahoma City, OK
American College of Cardiology Oklahoma Chapter 2010 Annual Scientific Meeting Best Poster Award, April 10 2010, Oklahoma City, OK
American Heart Association’s Council on Basic Cardiovascular Sciences Abstract Travel Award, AHA Scientific Sessions 2009, Nov 14-18, 2009, Orlando, FL
“The James F. Hammarsten Award”, for best oral presentation, 16th Annual Department of Internal Medicine Stewart Wolf Resident’s Research Forum, University of Oklahoma Health Sciences Center, May 14 2008, Oklahoma City, OK
Southern Society for Clinical Investigation, Cardiovascular Case Reports Scholar, SSCI Annual Meeting, Feb 21-23, 2008, New Orleans, LA
American Federation for Medical Research, SAFMR/SSCI Trainee Research Award, SSCI Annual Meeting, Feb 8-10, 2007, New Orleans, LA
Southern Society for Clinical Investigation, Cardiovascular Case Reports Scholar, SSCI Annual Meeting, Feb 8-10, 2007, New Orleans, LA
University of Athens, Award for superior performance, 11/2003
State Scholarships Foundation, Greece, Scholarship for superior performance for the years 1996-2002
27th International Chemistry Olympiad, Beijing 1995, Bronze Medal


Grant Support:

OK-INBRE-Clinical and Translational Research Award (07/01/12-04/30/14)
“Non-invasive neuromodulation to suppress atrial fibrillation”; Role: PI

VA Merit Review 2010-2013: “Atrial Fibrillation in Hyperthyroidism: Active Antibodies to Autonomic Receptor”; Role: Co-Investigator

Publications:
Journals:

  1. Stavrakis S, Patel N, Te C, Golwala H, George A, Lozano P, Lazzara R. Development and validation of a prognostic index for risk stratification of patients with early repolarization. Ann Novinvasive Electrocardiol 2012 (in press). PMID: 

  2. Te CC, Stavrakis S, Lozano P, Reynolds D. Apparent acute reversible right ventricular pacing induced left ventricular dysfunction. J Cardiovasc Electrophysiol 2012 (in press). PMID:

  3. Dib C, Hanna EB, Chaudhry MA, Hennebry TA, Stavrakis S, Abu-Fadel MS. Culprit-Vessel Percutaneous Coronary Intervention Followed by Contralateral Angiography versus Complete Angiography in Patients with ST-Elevation Myocardial Infarction. Tex Heart Inst J. 2012;39:359-64. PMID: 22719144 

  4. Stavrakis S, Garabelli P, Reynolds DW. Cardiac resynchronization therapy after atrioventricular junction ablation for symptomatic atrial fibrillation: a meta-analysis. Europace 2012 (in press). PMID: 22696519

  5. Mao J, Scherlag BJ, Liu Y, Fan Y, Varma V, Stavrakis S, Po SS. The atrial neural network as a substrate for atrial fibrillation. J Interv Card Electrophysiol 2012;39:359-64. PMID: 2269576

  6. Stavrakis S, Scherlag BJ, Po SS. Autonomic modulation: an emerging paradigm for the treatment of cardiovascular diseases. Circ Arrhythm Electrophysiol 2012;5:247-8. PMID: 22511657

  7. Stavrakis S, Scherlag BJ, Fan Youqi, Liu Y, Liu Q, Mao J, Cai H, Lazzara R, Po SS. Anti-arrhythmic effects of vasostatin-1 in a canine model of atrial fibrillation. J Cardiovasc Electrophys 2012;23:771-7

  8. Stavrakis S, Pakala A, Thomas J, Chaudhry MA, Thadani U. Obesity, brain natriuretic peptide levels and mortality in patients hospitalized with heart failure and preserved left ventricular systolic function. Am J Med Sci 2012 (in press). PMID: 

  9. Hawkins BM, Stavrakis S, Rousan TA, Abu-Fadel MS, Schechter E. Coronary slow flow-prevalence and clinical correlates. Circ J 2012;76:936-42. PMID: 22293446 

  10. Yu X, Stavrakis S, Hill MA, Huang S, Reim S, Li H, Khan M, Hamlett S, Cunningham MW, Kem DC. Autoantibody Activation of Beta-Adrenergic and Muscarinic Receptors Contributes to an "Autoimmune" Orthostatic Hypotension. J Am Soc Hypertens 2012;6:40-7. PMID: 22130180 

  11. Hawkins BM, Golwala H, Stavrakis S, Abu-Fadel MS. Embolic protection device use and outcomes in subjects receiving saphenous vein graft interventions - a single center experience. J Invas Cardiol 2012;24:1-3. PMID: 22210580 

  12. Stavrakis S, Lazzara R, Thadani U. The benefit of cardiac resynchronization therapy and QRS duration: a meta-analysis. J Cardiovasc Electrophysiol 2012;23:163-8. PMID: 21815961 

  13. Stavrakis S, Madden G, Pokharel D, Po SS, Nakagawa H, Jackman WM, Sivaram CA. Transesophageal echocardiographic assessment of pulmonary veins and left atrium in patients undergoing atrial fibrillation ablation. Echocardiography 2011;28:775-81. PMID: 21752091 

  14. Pappy R, Stavrakis S, Hennebry TA, Abu-Fadel MS. Effect of statin therapy on contrast-induced nephropathy after coronary angiography:  a meta-analysis. Int J Cardiol 2011;151:348-53. PMID: 21636154 

  15. Patel N, Golwala H, Stavrakis S, Schechter E. Sertraline induced ventricular tachycardia. Am J Ther 2011. PMID: 21768871 

  16. Stavrakis S, Stoner JA, Azar M, Wayangankar S, Thadani U. Aspirin for primary prevention of cardiovascular events in patients with diabetes: a meta-analysis. Am J Med Sci 2011;341:1–9. PMID: 21191260 

  17. Stavrakis S, Terrovitis J, Tsolakis E, Drakos S, Dalianis A, Bonios M, Koudoumas D, Malliaras K, Nanas J. Retrograde coronary blood flow predicts no-reflow and infarct size in a porcine ischemia reperfusion model. J Cardiovasc Trans Res 2011;4:99-105. PMID: 21153063 

  18. Stavrakis S, Madden GW, Stoner JA, Sivaram CA. Transesophageal echocardiography for the diagnosis of pulmonary vein stenosis after catheter ablation of atrial fibrillation: a systematic review. Echocardiography 2010;27:1141-6. PMID: 20678129 

  19. Stavrakis S, Kem DC, Patterson E, Lozano P, Huang S, Szabo B, Madeleine CW, Lazzara R, Yu X. Opposing Cardiac Effects of Autoantibody Activation of Beta-Adrenergic and M2 Muscarinic Receptors in Cardiac Related Diseases. Int J Cardiol 2011;148:331-6. PMID: 20053466 

  20. Stavrakis S, Yu X, Patterson E, Huang S, Hamlett SR, Chalmers L, Pappy R, Cunningham CW, Morshed SA, Davies TF, Lazzara R, Kem DC. Activating autoantibodies to the beta1-adrenergic and M2 muscarinic receptors facilitate atrial fibrillation in patients with Graves’ hyperthyroidism. J Am Coll Cardiol 2009;54:1309-16. PMID: 19778674 

  21. Yu X, Patterson E, Stavrakis S, Huang S, DeAos I, Hamlett S, Cunningham MW, Lazzara R, Kem DC. Development of cardiomyopathy and atrial tachyarrhythmias associated with activating autoantibodies to beta-adrenergic and muscarinic receptors. J Am Soc Hypertens 2009;3:133-140. PMID: 20409953 

  22. Kem DC, Yu X, Patterson E, Huang S, Stavrakis S, Szabo B, Olansky L, McCauley J, Cunningham MW. Autoimmune hypertensive syndrome. Hypertension2007;50:829-834. PMID: 17923587 

  23. Tiniakos D, Anagnostou V, Stavrakis S, Karandrea D, Agapitos E, Kittas C. Ontogeny of intrinsic innervation in the human kidney. Anat Embryol (Berl) 2004;209:41-47. PMID: 15480775

Abstracts:

  1. Stavrakis S, Scherlag BJ, Fan Y, Liu Y, Mao J, Varma V, Lazzara R, Po SS. Inhibition of atrial fibrillation inducibility by low level vagus nerve stimulation: the role of nitric oxide signaling pathway. AHA 2011 Scientific Sessions, Orlando, FL, Nov 12-16, 2011 (oral presentation)

  2. Stavrakis S, Patel N, Te C, Golwala H, Lozano P, Lazzara R. Development and validation of a prognostic index for risk stratification of patients with early repolarization. AHA 2011 Scientific Sessions, Orlando, FL, Nov 12-16, 2011 (oral presentation)

  3. Stavrakis S, Stoner JA, Thadani U. Impact on Short- and Long-Term Mortality of Invasive Versus Conservative Strategy in Non--ST-Elevation Acute Coronary Syndromes: A Meta-analysis. AHA Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke 2011 Scientific Sessions, Washington, DC, May 12-14, 2011 (poster presentation) 

  4. Stavrakis S, Lazzara R, Thadani U. The benefit of cardiac resynchronization therapy and QRS duration: a meta-analysis. Heart Rhythm 2011;8:S14-S15. Heart Rhythm 2011 Scientific Sessions, San Francisco, CA, May 4-7, 2011 (oral presentation)

  5. Stavrakis S, Scherlag BJ, Fan Y, Liu Y, Heng C, Lazzara R, Po SS. Suppression of atrial fibrillation inducibility by vasostatin-1. Heart Rhythm 2011;8:S265 (poster presentation) 

  6. Hawkins BM, Golwala H, Stavrakis S, Abu-Fadel MS. Embolic protection device use and outcomes in subjects receiving saphenous vein graft interventions. J Am Coll Cardiol 2011;57:E1054 

  7. Pappy R, Stavrakis S, Hennebry TA, Abu-Fadel MS. Beneficial effects of statin therapy on the incidence of contrast-induced nephropathy after coronary angiography: a meta-analysis.  J Am Coll Cardiol 2011;57:E578 

  8. Stavrakis S, Hawkins B, Thadani U. Routine early invasive strategy after thrombolysis does not reduce mortality in patients with ST-segment elevation myocardial infarction: a meta-analysis of randomized clinical trials. AHA 2010 Scientific Sessions, Chicago, IL, Nov 13-17, 2010 (oral presentation)

  9. Stavrakis S, Yu X, Huang S, Cunningham M, Kem DC, Patterson E. Facilitation of Triggered Firing in Superfused Canine Pulmonary Veins By Activating Antibodies to Beta Adrenergic and Muscarinic Receptors in Serum From Patients With Graves’ Disease. Circulation 2009;120:S664-S665. AHA 2009 Scientific Sessions, Orlando, FL, Nov 14-18, 2010 (oral presentation)

  10. Stavrakis S, Yu X, Huang S, Pappy R, Hamlett S, Patterson E, Cunningham MW, Kem DC. Prominent effects of activating autoantibodies to beta1 adrenergic and M2 muscarinic receptors in atrial fibrillation compared to heart failure. J Am Coll Cardiol. 2009;58:A113

  11. Yu X, Stavrakis S, Hamlett S, Huang S, Patterson E, Cunningham M, Kem DC. Autoantibody activation of beta adrenergic and muscarinic receptors contributes to an “autoimmune” postural hypotension. Circulation. 2008;118:S549. AHA 2008 Scientific Sessions, New Orleans, LA, Nov 8-12, 2008 (oral presentation)

  12. Stavrakis S, Pappy R, Patterson E, DeAos I, Cunninham MW, Kem DC, Yu X. Autoantibody activation of beta adrenergic and M2 muscarinic receptors in hyperthyroid patients with in atrial fibrillation. J Am Coll Cardiol. 2008;51:A9

  13. Stavrakis S, Te C, Murray C, Lozano P. Transient left apical ballooning syndrome: a mimic of acute myocardial infarction. J Invest Med. 2008;56:354

  14. Pappy R, Stavrakis S, Patterson E, DeAos I, Cunninham MW, Kem DC, Yu X. Hyperthyroidism and Activating Autoantibodies to Beta Adrenergic and M2 Muscarinic Receptors: Synergistic Role in Atrial Fibrillation. J Invest Med. 2008;56:425-426

  15. Tsagalou E, Pierrakos C, Lazaris N, Charitos E, Savvari P, Marinakis S, Pozios H, Venetsanakos J, Maroulidis G, Stavrakis S, Anastasiou-Nana M. Time course of microvascular obstruction after acute myocardial infarction: Rapid expansion of anatomic no-reflow during reperfusion in the pig. J Am Coll Cardiol. 2007;49:221A

  16. Stavrakis S, Yu X, Huang S, Patterson E, Szabo B, Cunningham MW, Kem DC. Autoantibody Activation of Beta1/2 Adrenergic and M2 Muscarinic Receptors in Diabetic Cardiomyopathy. Hypertension. 2007;50:E146-E147

  17. Stavrakis S, Yu X, Huang S, Patterson E, Baba A, Szabo B, Cunningham MW, Kem DC.Pathophysiologic role of M2 muscarinic receptor autoantibodies in patients with diabetic cardiomyopathyJ Invest Med. 2007;55:S276

  18. Stavrakis S, Vasamreddy CR, Lozano P. Spontaneous resolution of ST-segment elevation: a case report. J Invest Med. 2007;55:S250-S251

  19. Charitos E, Papazoglou P, Tsolakis E, Xatziiliadis A, Stavrakis S, Venetsanakos I, Ntalianis A, Pierrakos C, Nanas J. Effects of levosimendan plus noradrenaline on coronary blood flow, myocardial infarct Size, and the extent of the no-reflow phenomenon in an experimental model of ischemia-reperfusion. Circ Res 2006;99:E41

  20. Bonios M, Ntalianis A, Stavrakis S, Drakos S, Savvari P, Koudoumas D, Dolou P, Pierrakos C, Papalois A, Nanas J. Intra-aortic balloon counterpulsation during myocardial reperfusion increases coronary blood flow and myocardial salvage: experimental study. J Am Coll Cardiol 2005;45:253A

  21. Terrovitis J, Tsagalou E, Papazoglou P, Tanos G, Mponios M, Charitos E, Stavrakis S, Anastasiou-Nana M. Fifteen minutes latent period for bolus intravenous amiodarone to exert its antiarrhythmic effect – experimental study. Eur Hear J 2004;24:36