Low Testosterone

Low testosterone is common, affects men of all ages, and can negatively impact a man’s quality of life. Low T symptoms include:

  • Low energy and fatigue
  • Decreased interest in sex (low libido)
  • Decreased exercise capacity
  • Fertility issues*
  • Decreased concentration, focus, and/or memory
  • Irritability/moodiness
  • Problems with sex, including erectile dysfunction
  • Sleep disturbance
  • Weight gain and/or loss of muscle mass

*Patients trying to achieve pregnancy will be offered testosterone-stimulating drugs only. Testosterone therapy can decrease sperm production.

Treatments include:

  • Injectable testosterone (including testosterone enanthate and cypionate) – we teach patients to inject themselves at home, not requiring frequent office visits.
  • Topical testosterone – a variety of topical formulations are available and often covered by insurance.
  • Subcutaneous Pellets – tiny pellets can be placed underneath the skin of the buttocks, which slowly dissolve over four months.
  • Long-lasting injectable testosterone – must be administered by a health care professional, but only requires five shots a year to maintain treatment levels.
  • Testosterone patches – offers a topical option without the risk of transference to a loved one. The most common side effect is skin irritation.
  • Testosterone stimulating alternatives – medications such as hCG, clomiphene citrate, anastrozole, and others can be administered to stimulate production of one’s own testosterone or used as adjunctive medications along with testosterone depending on the patient’s specific condition and goals.

OU Medicine