OU Medicine News

OU College of Medicine Researcher Earns Federal Grant to Study Molecule’s Potential as Cancer Drug Target

      OKLAHOMA CITY -- The tragic irony about breast cancer is that patients usually don’t die because of the initial tumor, but when the cancer metastasizes.

      That reality drives researchers to find a way to keep cancer from spreading. Ralf Janknecht, Ph.D., a researcher in the Department of Cell Biology at the OU College of Medicine, has been analyzing the behavior of a particular molecule that is over produced in breast cancer. This year, he was awarded a five-year, $1.78 million grant from the National Cancer Institute to further evaluate the molecule’s potential in reducing cancer metastasis. His discoveries thus far suggest that the molecule, called DNPH1, has the capability to serve as a drug target for stopping the spread of cancer.

   To read more about the research, visit the Stephenson Cancer Center website


Founded in 1910, the University of Oklahoma College of Medicine trains the next generation of healthcare professionals. With campuses in Oklahoma City and Tulsa, the College of Medicine offers the state’s only Doctor of Medicine degree program and a nationally competitive Physician Assistant program. For more information, visit oumedicine.com/collegeofmedicine.



OU Medicine — along with its academic partner, the University of Oklahoma Health Sciences Center — is the state’s only comprehensive academic health system of hospitals, clinics and centers of excellence. With 11,000 employees and more than 1,300 physicians and advanced practice providers, OU Medicine is home to Oklahoma’s largest physician network with a complete range of specialty care. OU Medicine serves Oklahoma and the region with the state’s only freestanding children’s hospital, the only National Cancer Institute-Designated Stephenson Cancer Center and Oklahoma’s flagship hospital, which serves as the state’s only Level 1 trauma center. OU Medicine’s mission is to lead healthcare in patient care, education and research. To learn more, visit oumedicine.com.